Telomeres may be the best measure of biological age.
They hold remarkable information about the path of our health and may be the single most important biomarker of aging. Recent scientific discoveries show how extraordinarily high concentrations of select antioxidants can help preserve and strengthen the ability of telomeres to maintain health at the cellular level where the aging process begins.
Every human cell has 23 pairs of chromosomes containing DNA that provide instructions for cell division and function. Telomeres are protective caps on the ends of chromosomes that help maintain DNA integrity as the trillions of cells in the body constantly divide.
Nobel prize-winning research links aging to the gradual shortening of telomeres, which over time may result in impaired cell function or cellular senescence (cell death).1 Research shows that oxidative stress is perhaps an even bigger threat to telomere health.2
High levels of unstable molecules called reactive oxygen species – a product of cellular metabolism – damage telomeric DNA, accelerates telomere shortening and is a primary cause of premature cellular senescence that is a factor in numerous age-related diseases.3 Damaged telomeres can create “zombie cells” that are still alive but can’t function. These cells can impair tissue healing and immune function, as well as promote inflammation.4
Researchers can now determine cellular health and age by comparing the average length of an individual’s telomeres with those of the general population. This age measurement is also known as TeloYears. A person’s TeloYears age may be older or younger than their real age. Age at the cellular level may be a better indicator of how well an individual is aging than actual age.
Telos95 is the result of years of research involving many purified natural organic compounds. Its effectiveness at lengthening telomeres and reducing cellular age (TeloYears) was scientifically validated in both in vitro and clinical studies using two widely accepted methodologies.
The preclinical research conducted at Life Length Laboratories, a world-renowned academic center for telomere research. Analysis with the lab’s proprietary TAT technology showed that cells treated with Telos95 had significant increases in median telomere length after 10 days.5
A randomized, peer-reviewed clinical study reported similar results. In the study, 50 healthy volunteers consumed one capsule (95mgs) or two capsules (190mgs) of Telo95 daily over six months. Blood samples were taken at the beginning and end of the study period for comparison.6
The blood samples were analyzed with the Cawthon qPCR assay to determine average telomere length (ATL) and to assign a TeloYear age to each subject based on the comparison of their ATL to others in their same age and gender.7
Reduction in TeloYears (Cellular Age). Study participants taking 95 mgs of Telos95 daily reduced their cellular age by an average of 7.43 years. (Subjects taking 190 mgs reduced their cellular age 8.52 years.) 8
In just six months, study subjects taking Telos95 daily had a significant increase in median telomere length.9
Researchers found that subjects taking one capsule of Telos95 significantly reduced their TeloYear Age an average of 7.43 years. Their ATL showed a baseline measurement of 0.85 increased to 0.95 by the end of the study. Volunteers taking two capsules daily decreased their TeloYears by 8.52 years and increased their ATL to 0.94 from 0.82.10
In just six months, study participants taking 95 mgs of Telos95 daily reduced their cellular age by an average of 7.43 years. (Subjects taking 190 mgs reduced their cellular age 8.52 years.)11
Study subjects taking Telos95 daily had a significant increase in telomere length in just six months.12
Telos95 is an innovative ingredient in the new science of aging. Ideal for a wide range of supplement applications, including capsules, tablets, gummies, stick packs and beverages.
Nobel-prize winning research has validated the link between telomere length and the aging process. Download this infographic to learn more about the role of telomeres in protecting DNA and healthy cell division, as well as how to protect telomeres and slow the aging process.
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References
1 Telomere length variations in aging and age-related diseases. Curr Aging Sci. 2014;7(3):161-7.
2,3 Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening. Nature Structural & Molecular Biology. Vol 29, 639–652. July 2022.
4 Cells become zombies when the ends of their chromosomes are damaged, Apple News. Aug 2022.
5-12 A randomized-controlled clinical study of Telos95®, a novel antioxidative dietary supplement, on the shortening of telomere length in healthy volunteers. HealthMED – Volume 13 / Number 1 / 2019.
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