60 day human clinical study confirms kollaGen II-xs™ Hydrolysate efficacy for joint & connective tissue disorders!

Murrieta, California – February 24, 2014 - Certified Nutraceuticals, Inc. is pleased to announce the positive results of the 60 day Human Clinical Study for the efficacy of kollaGen II-xs™ U.S. Patent #8,344,106 B1- Avian (Chicken) Sternum Collagen Type II powder Hydrolysate. This is the natural blend of Hyaluronic Acid, Chondroitin, Glucosamine compounds, and amino acids which basically are the building blocks of joint cartilage. The process preserves all important nutrients and capable amino acids in order for kollaGen II-xs™ to be effective after enzyme digestion in the human digestive tract. The compositional makeup of kollaGen II-xs™ produced extraordinary clinical therapeutic value for connective tissue disorders and improved the mobility and activity for individuals with joint conditions.

For this study we chose 20 patients' ages 17 years to 81 years (10 males / 10 females) with confirmed joint damage and cartilage injuries, diagnosed with imaging/scoping with low to high pain scales. The optimal dosage administered is 1500mg - 2500mg daily dietary supplement taken with citric juice on an empty stomach.

Significant Scientific Findings of Positive Clinical Responses:

Targeted Clinical Response Results

Supplementation with kollaGen II-xs™ produced a significant treatment response at seven days for flexibility (33.3% increase; P = 0.035) and at 60 days for general pain (91.6% reduction; P = 0.005), flexibility (68.5% increase; P = 0.004) and range of motion associated pain (76.1% reduction; P = 0.011). The substantial treatment response continued through 60 days for pain (78.8% reduction; P = 0.001). There were no adverse events reported during the study and the treatment was reported to be well tolerated by study participants.

Conclusion

kollaGen II-xs™ is a safe novel preparation when taken at a dosage of 500mg 4 times per day. The benefits are clearly defined as a treatment for joint inflammation, secondary mobility and other tertiary effects. It clearly benefited arthritic participants (rheumatoid and osteoarthritis alike) and clearly demonstrates a non-toxic approach to the treatment of arthritic diseases. kollaGen II-xs™ has extremely viable crucial amino acids and mucopolysaccarides containing cartilage matrix glycoprotein (CMGP). Cartilage matrix glycoprotein enhances the antioxidant protection within joints by carrying a crucial component to the chondrocytes. Chondrocytes are small cells interspersed within the cartilage matrix of joints. The chondrocytes produce new collagen and mucopolysaccharides creating a cushion effect providing lubrication. The composition of this substance utilizes water extraction in manufacturing to maintain the integrity of sensitive molecules without utilizing harsh chemicals.

KollaGen II-xs™ participants found in particular better overall healing after minor injuries. The study noted that some forms of facial skin softening was reported in 13 participants post questionnaire (more in the >40 age of participants).

This study demonstrates that kollaGen II-xs™ is a likely viable treatment option for the management of joint and connective tissue disorders. The effects of this study are clearly life altering for the better. Therefore at a dosage of 1500- 2400 mg daily significantly reduced pain and inflammatory response at a rapid onset continuously from initialization of trial to 60 days.

The Human Clinical Trial is performed by Morton Scientific Group of Cambridge, Ontario, Canada and overseen by qualified Medical Doctors. Certified Nutraceuticals supplies the world market with kollaGen II-xs™ in bulk powder which is manufactured at FDA - USDA approved facility and proudly promote the products as Made in USA.

Our advantage is the exclusive proprietary water extraction technology process to extract denatured Avian Sternum Collagen Type II Powder without the use of solvent (ethanol) or harsh chemicals. This process preserves important nutrients and molecules to yield more Hyaluronic Acid (HA) and more Chondroitin for optimum assimilation to help damaged cartilage. We also used natural enzymes to solubilize (Hydrolysate) the product for maximum hydration and to control HA and Chondroitin Molecular Weight (MW).

kollaGen II-xs™ powder is 100% water soluble and can be made easily into capsules, tablets, beverages, functional foods and cosmetic applications.